7N3K

Oridonin-bound SARS-CoV-2 Nsp9

Summary for 7N3K

Entry DOI	10.2210/pdb7n3k/pdb
Descriptor	Non-structural protein 9, (1beta,6beta,7beta,8alpha,9beta,10alpha,13alpha,14R,16beta)-1,6,7,14-tetrahydroxy-7,20-epoxykauran-15-one, SULFATE ION (3 entities in total)
Functional Keywords	sars-cov-2, nsp9, rna binding complex, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
Total number of polymer chains	8
Total formula weight	120056.98
Authors	Littler, D.R.,Gully, B.S.,Rossjohn, J. (deposition date: 2021-06-01, release date: 2021-10-27, Last modification date: 2023-10-18)
Primary citation	Littler, D.R.,Liu, M.,McAuley, J.L.,Lowery, S.A.,Illing, P.T.,Gully, B.S.,Purcell, A.W.,Chandrashekaran, I.R.,Perlman, S.,Purcell, D.F.J.,Quinn, R.J.,Rossjohn, J. A natural product compound inhibits coronaviral replication in vitro by binding to the conserved Nsp9 SARS-CoV-2 protein. J.Biol.Chem., 297:101362-101362, 2021 Cited by PubMed: 34756886 DOI: 10.1016/j.jbc.2021.101362 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation