7N33
SARS-CoV-2 Nsp15 endoribonuclease pre-cleavage state
Summary for 7N33
Entry DOI | 10.2210/pdb7n33/pdb |
Related | 7N06 |
EMDB information | 24101 24137 |
Descriptor | Uridylate-specific endoribonuclease, RNA (5'-R(*A)-D(*(UFT))-R(P*A)-3') (2 entities in total) |
Functional Keywords | endoribonuclease, viral protein, viral protein-rna complex, viral protein/rna |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) More |
Total number of polymer chains | 12 |
Total formula weight | 248667.97 |
Authors | Frazier, M.N.,Dillard, L.B.,Krahn, J.M.,Stanley, R.E. (deposition date: 2021-05-31, release date: 2021-06-09, Last modification date: 2024-05-29) |
Primary citation | Frazier, M.N.,Dillard, L.B.,Krahn, J.M.,Perera, L.,Williams, J.G.,Wilson, I.M.,Stewart, Z.D.,Pillon, M.C.,Deterding, L.J.,Borgnia, M.J.,Stanley, R.E. Characterization of SARS2 Nsp15 nuclease activity reveals it's mad about U. Nucleic Acids Res., 49:10136-10149, 2021 Cited by PubMed: 34403466DOI: 10.1093/nar/gkab719 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.5 Å) |
Structure validation
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