7N06
SARS-CoV-2 Nsp15 endoribonuclease post-cleavage state
Summary for 7N06
Entry DOI | 10.2210/pdb7n06/pdb |
EMDB information | 24101 |
Descriptor | Uridylate-specific endoribonuclease, RNA (5'-R(*AP*UP*A)-3') (3 entities in total) |
Functional Keywords | endoribonuclease, viral protein, hydrolase-rna complex, hydrolase/rna |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) More |
Total number of polymer chains | 12 |
Total formula weight | 260669.48 |
Authors | Frazier, M.N.,Dillard, L.B.,Krahn, J.M.,Stanley, R.E. (deposition date: 2021-05-25, release date: 2021-06-02, Last modification date: 2024-05-29) |
Primary citation | Frazier, M.N.,Dillard, L.B.,Krahn, J.M.,Perera, L.,Williams, J.G.,Wilson, I.M.,Stewart, Z.D.,Pillon, M.C.,Deterding, L.J.,Borgnia, M.J.,Stanley, R.E. Characterization of SARS2 Nsp15 nuclease activity reveals it's mad about U. Nucleic Acids Res., 49:10136-10149, 2021 Cited by PubMed: 34403466DOI: 10.1093/nar/gkab719 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.2 Å) |
Structure validation
Download full validation report