7MYX
Crystal structure of the PH domain (R86A) of Akt1
Summary for 7MYX
Entry DOI | 10.2210/pdb7myx/pdb |
Descriptor | RAC-alpha serine/threonine-protein kinase (2 entities in total) |
Functional Keywords | kinase, signaling protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 14456.34 |
Authors | Bae, H.,Park, E.,Cole, P.A.,Eck, M.J. (deposition date: 2021-05-22, release date: 2022-11-09, Last modification date: 2023-10-18) |
Primary citation | Bae, H.,Viennet, T.,Park, E.,Chu, N.,Salguero, A.,Eck, M.J.,Arthanari, H.,Cole, P.A. PH domain-mediated autoinhibition and oncogenic activation of Akt. Elife, 11:-, 2022 Cited by PubMed: 35968932DOI: 10.7554/eLife.80148 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.39 Å) |
Structure validation
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