7MYA
Structure of proline utilization A with the FAD covalently-modified by 1,3-dithiolane
Summary for 7MYA
Entry DOI | 10.2210/pdb7mya/pdb |
Descriptor | Bifunctional protein PutA, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-5-[5-(1,3-dithiolan-2-yl)-7,8-dimethyl-2,4-dioxo-1,3,4,5-tetrahydrobenzo[g]pteridin-10(2H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate, MAGNESIUM ION, ... (9 entities in total) |
Functional Keywords | flavoenzyme, rossmann fold, proline dehydrognease, aldehyde dehydrogenase, proline catabolism, substrate channeling, bifunctional enzyme, oxidoreductase |
Biological source | Sinorhizobium meliloti SM11 |
Total number of polymer chains | 2 |
Total formula weight | 268868.01 |
Authors | Tanner, J.J.,Campbell, A.C. (deposition date: 2021-05-20, release date: 2021-09-29, Last modification date: 2023-10-18) |
Primary citation | Campbell, A.C.,Prater, A.R.,Bogner, A.N.,Quinn, T.P.,Gates, K.S.,Becker, D.F.,Tanner, J.J. Photoinduced Covalent Irreversible Inactivation of Proline Dehydrogenase by S-Heterocycles. Acs Chem.Biol., 16:2268-2279, 2021 Cited by PubMed: 34542291DOI: 10.1021/acschembio.1c00427 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.56 Å) |
Structure validation
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