7MXQ
Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (r-1)
Summary for 7MXQ
Entry DOI | 10.2210/pdb7mxq/pdb |
Descriptor | Exonuclease 1, DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), ... (6 entities in total) |
Functional Keywords | human exonuclease 1 complex with dna, hydrolase, hydrolase-dna complex, hydrolase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 47484.22 |
Authors | Shi, Y.,Beese, L.S. (deposition date: 2021-05-19, release date: 2023-05-10, Last modification date: 2023-10-25) |
Primary citation | Shi, Y.,Hellinga, H.W.,Beese, L.S. Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities To Be Published, |
Experimental method | X-RAY DIFFRACTION (3.23 Å) |
Structure validation
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