7MX9

Crystal structure of the SARS-CoV-2 ORF8 accessory protein

Summary for 7MX9

• Entry DOI: 10.2210/pdb7mx9/pdb
• Descriptor: ORF8 protein (2 entities in total)
• Functional Keywords: sars-cov-2, covid19, orf8, immunoglobulin fold, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
• Total number of polymer chains: 1
• Total formula weight: 12906.72

Authors

Bailey-Elkin, B.A.,Stetefeld, J. (deposition date: 2021-05-18, release date: 2023-01-25, Last modification date: 2024-10-23)

• Primary citation: Hamdorf, M.,Imhof, T.,Theobald, S.J.,Simonis, A.,Di Cristanziano, V.,Gieselmann, L.,Dewald, F.,Lehmann, C.,Augustin, M.,Klein, F.,Alejandre Alcazar, M.A.,Rongisch, R.,Fabri, M.,Cursiefen, C.,Rybniker, J.,Bailey-Elkin, B.A.,Stetefeld, J.,Koch, M.,Bock, F.; The unique ORF8 protein of SARS-CoV-2 binds to human dendritic cells and induces a cytokine storm; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.6 Å)