7MWX

Structure of the core ectodomain of the hepatitis C virus envelope glycoprotein 2 with tamarin CD81

Summary for 7MWX

• Entry DOI: 10.2210/pdb7mwx/pdb
• Descriptor: Core protein precursor eE2, 2A12 Fab Heavy Chain, 2A12 Fab Light Chain, ... (7 entities in total)
• Functional Keywords: glycoprotein, receptor, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Hepacivirus C; More
• Total number of polymer chains: 8
• Total formula weight: 175223.96

Authors

Kumar, A.,Hossain, R.A.,Yost, S.A.,Bu, W.,Wang, Y.,Dearborn, A.D.,Grakoui, A.,Cohen, J.I.,Marcotrigiano, J. (deposition date: 2021-05-17, release date: 2021-09-15, Last modification date: 2023-10-18)

• Primary citation: Kumar, A.,Hossain, R.A.,Yost, S.A.,Bu, W.,Wang, Y.,Dearborn, A.D.,Grakoui, A.,Cohen, J.I.,Marcotrigiano, J.; Structural insights into hepatitis C virus receptor binding and entry.; Nature, 598:521-525, 2021; PubMed: 34526719; DOI: 10.1038/s41586-021-03913-5

Experimental method

X-RAY DIFFRACTION (3.32 Å)