7MWX

Structure of the core ectodomain of the hepatitis C virus envelope glycoprotein 2 with tamarin CD81

7MWX の概要

• エントリーDOI: 10.2210/pdb7mwx/pdb
• 分子名称: Core protein precursor eE2, 2A12 Fab Heavy Chain, 2A12 Fab Light Chain, ... (7 entities in total)
• 機能のキーワード: glycoprotein, receptor, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Hepacivirus C; 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 175223.96

構造登録者

Kumar, A.,Hossain, R.A.,Yost, S.A.,Bu, W.,Wang, Y.,Dearborn, A.D.,Grakoui, A.,Cohen, J.I.,Marcotrigiano, J. (登録日: 2021-05-17, 公開日: 2021-09-15, 最終更新日: 2023-10-18)

• 主引用文献: Kumar, A.,Hossain, R.A.,Yost, S.A.,Bu, W.,Wang, Y.,Dearborn, A.D.,Grakoui, A.,Cohen, J.I.,Marcotrigiano, J.; Structural insights into hepatitis C virus receptor binding and entry.; Nature, 598:521-525, 2021; PubMed: 34526719; DOI: 10.1038/s41586-021-03913-5

実験手法

X-RAY DIFFRACTION (3.32 Å)