7MQV

Crystal structure of truncated (ACT domain removed) prephenate dehydrogenase tyrA from Bacillus anthracis in complex with NAD

Summary for 7MQV

• Entry DOI: 10.2210/pdb7mqv/pdb
• Related: 6U60
• Descriptor: Prephenate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, GLYCEROL, ... (5 entities in total)
• Functional Keywords: structural genomics, center for structural genomics of infectious diseases, csgid, hydrolase
• Biological source: Bacillus anthracis
• Total number of polymer chains: 4
• Total formula weight: 140782.90

Authors

Shabalin, I.G.,Gritsunov, A.,Gabryelska, A.,Czub, M.P.,Grabowski, M.,Cooper, D.R.,Christendat, D.,Minor, W.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2021-05-06, release date: 2021-05-19, Last modification date: 2023-10-18)

• Primary citation: Shabalin, I.G.,Hou, J.,Christendat, D.,Minor, W.; The crystal structure of Bacillus anthracis prephenate dehydrogenase identified an ACT regulatory domain and a novel mode of metabolic regulation for proteins within the prephenate dehydrogenase family of enzyme; to be published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)