7MP2

CRYSTAL STRUCTURE OF NATIVE BOVINE ARRESTIN 1 IN COMPLEX WITH 1D-MYO-INOSITOL 1,5-BISDIPHOSPHATE TETRAKISPHOSPHATE (1,5-PP IP4)

7MP2 の概要

• エントリーDOI: 10.2210/pdb7mp2/pdb
• 分子名称: S-arrestin, (1R,3S,4R,5S,6R)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl bis[trihydrogen (diphosphate)] (3 entities in total)
• 機能のキーワード: gpcr, rhodopsin, phototransduction, inositol, 1, 5pp-ip4, ip8, protein binding
• 由来する生物種: Bos taurus (Bovine)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 186259.09

構造登録者

Sander, C.L.,Palczewski, K.,Kiser, P.D. (登録日: 2021-05-04, 公開日: 2021-10-13, 最終更新日: 2023-10-18)

• 主引用文献: Sander, C.L.,Luu, J.,Kim, K.,Furkert, D.,Jang, K.,Reichenwallner, J.,Kang, M.,Lee, H.J.,Eger, B.T.,Choe, H.W.,Fiedler, D.,Ernst, O.P.,Kim, Y.J.,Palczewski, K.,Kiser, P.D.; Structural evidence for visual arrestin priming via complexation of phosphoinositols.; Structure, 30:263-277.e5, 2022; PubMed: 34678158; DOI: 10.1016/j.str.2021.10.002

実験手法

X-RAY DIFFRACTION (3 Å)