7MP1

CRYSTAL STRUCTURE OF NATIVE BOVINE ARRESTIN 1 IN COMPLEX WITH 1,5-DI-METHYLENEBISPHOSPHONATE INOSITOL TETRAKISPHOSPHATE (1,5-PCP-IP4)

7MP1 の概要

• エントリーDOI: 10.2210/pdb7mp1/pdb
• 分子名称: S-arrestin, {[(1R,3S,4S,5R,6S)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl]bis[oxy(hydroxyphosphoryl)methanediyl]}bis(phosphonic acid) (3 entities in total)
• 機能のキーワード: gpcr, rhodopsin, phototransduction, inositol, 5pp-ip5, ip7, protein binding
• 由来する生物種: Bos taurus (Bovine)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 185419.37

構造登録者

Sander, C.L.,Palczewski, K.,Kiser, P.D. (登録日: 2021-05-04, 公開日: 2021-10-13, 最終更新日: 2023-10-18)

• 主引用文献: Sander, C.L.,Luu, J.,Kim, K.,Furkert, D.,Jang, K.,Reichenwallner, J.,Kang, M.,Lee, H.J.,Eger, B.T.,Choe, H.W.,Fiedler, D.,Ernst, O.P.,Kim, Y.J.,Palczewski, K.,Kiser, P.D.; Structural evidence for visual arrestin priming via complexation of phosphoinositols.; Structure, 30:263-277.e5, 2022; PubMed: 34678158; DOI: 10.1016/j.str.2021.10.002

実験手法

X-RAY DIFFRACTION (2.66 Å)