7MOM
Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) in complex with a metaphosphate intermediate
Summary for 7MOM
Entry DOI | 10.2210/pdb7mom/pdb |
Descriptor | Tyrosine-protein phosphatase DSP1, PHOSPHITE ION, BETA-MERCAPTOETHANOL, ... (4 entities in total) |
Functional Keywords | inositol, inositol pyrophosphate, transferase, hydrolase, cell-signaling, phosphatase, substrate recognition, reaction mechanism, intermediate, phosphate, metaphosphate, molecular dynamic simulation, self-activation, catalytic water |
Biological source | Arabidopsis thaliana (Mouse-ear cress) |
Total number of polymer chains | 2 |
Total formula weight | 39710.01 |
Authors | Wang, H.,Shears, S.B. (deposition date: 2021-05-01, release date: 2022-03-02, Last modification date: 2024-05-22) |
Primary citation | Wang, H.,Perera, L.,Jork, N.,Zong, G.,Riley, A.M.,Potter, B.V.L.,Jessen, H.J.,Shears, S.B. A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop. Nat Commun, 13:2231-2231, 2022 Cited by PubMed: 35468885DOI: 10.1038/s41467-022-29673-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
Download full validation report