7MMZ

Crystal Structure of Acetyl-coenzyme A synthetase from Legionella pneumophila Philadelphia 1 in complex with ethyl-AMP

7MMZ の概要

• エントリーDOI: 10.2210/pdb7mmz/pdb
• 分子名称: Acetyl-coenzyme A synthetase, 5'-O-[(S)-ethoxy(hydroxy)phosphoryl]adenosine, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: ssgcid, acetyl-coenzyme a synthetase, acs-1, legionella pneumophila, structural genomics, seattle structural genomics center for infectious disease, ligase
• 由来する生物種: Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 71068.82

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2021-04-30, 公開日: 2021-05-26, 最終更新日: 2023-10-25)

• 主引用文献: DeBouver, N.D.,Bolejack, M.J.,Esan, T.E.,Krysan, D.J.,Hagen, T.J.,Abendroth, J.; Bacterial structural genomics target enabled by a recently discovered potent fungal acetyl-CoA synthetase inhibitor.; Acta Crystallogr.,Sect.F, 2023; PubMed: 37223974; DOI: 10.1107/S2053230X23003801

実験手法

X-RAY DIFFRACTION (2.4 Å)