7MM1
PTP1B in complex with TCS401 by Native S-SAD at Room Temperature
Summary for 7MM1
Entry DOI | 10.2210/pdb7mm1/pdb |
Related | 7L84 7LVC |
Descriptor | Tyrosine-protein phosphatase non-receptor type 1, 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total) |
Functional Keywords | protein tyrosine phosphatase 1b, hydrolase, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 37860.11 |
Authors | Greisman, J.B.,Dalton, K.M.,Hekstra, D.R. (deposition date: 2021-04-29, release date: 2021-05-12, Last modification date: 2024-05-22) |
Primary citation | Greisman, J.B.,Dalton, K.M.,Sheehan, C.J.,Klureza, M.A.,Kurinov, I.,Hekstra, D.R. Native SAD phasing at room temperature. Acta Crystallogr D Struct Biol, 78:986-996, 2022 Cited by PubMed: 35916223DOI: 10.1107/S2059798322006799 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
Download full validation report