7MLM

Crystal structure of mouse TLR4/MD-2 in complex with sulfatides

7MLM の概要

• エントリーDOI: 10.2210/pdb7mlm/pdb
• 分子名称: Toll-like receptor 4,Variable lymphocyte receptor B, Lymphocyte antigen 96, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: innate immunity, endogenous ligands, toll-like receptors, immune system
• 由来する生物種: Mus musculus (Mouse); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 97231.32

構造登録者

Su, L.,Beutler, B. (登録日: 2021-04-28, 公開日: 2021-07-28, 最終更新日: 2023-10-18)

• 主引用文献: Su, L.,Athamna, M.,Wang, Y.,Wang, J.,Freudenberg, M.,Yue, T.,Wang, J.,Moresco, E.M.Y.,He, H.,Zor, T.,Beutler, B.; Sulfatides are endogenous ligands for the TLR4-MD-2 complex.; Proc.Natl.Acad.Sci.USA, 118:-, 2021; PubMed: 34290146; DOI: 10.1073/pnas.2105316118

実験手法

X-RAY DIFFRACTION (2.104 Å)