7ML8
The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ001023038
Summary for 7ML8
Entry DOI | 10.2210/pdb7ml8/pdb |
Descriptor | Polymerase acidic protein, GLUTAMIC ACID, 5-hydroxy-N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-6-oxo-2-phenyl-1,6-dihydropyrimidine-4-carboxamide, ... (7 entities in total) |
Functional Keywords | nuclease, influenza, inhibitor resistance, viral protein, viral protein-inhibitor complex, viral protein/inhibitor |
Biological source | Influenza A virus (strain swl A/California/04/2009 H1N1) More |
Total number of polymer chains | 1 |
Total formula weight | 24635.67 |
Authors | Cuypers, M.G.,Slavish, P.J.,Yun, M.K.,Dubois, R.,Rankovic, Z.,White, S.W. (deposition date: 2021-04-27, release date: 2021-10-27, Last modification date: 2023-10-18) |
Primary citation | Cuypers, M.G.,Slavish, P.J.,Yun, M.K.,Dubois, R.,Rankovic, Z.,White, S.W. The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with St Jude compound AC067-19 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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