7ML8

The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ001023038

7ML8 の概要

• エントリーDOI: 10.2210/pdb7ml8/pdb
• 分子名称: Polymerase acidic protein, GLUTAMIC ACID, 5-hydroxy-N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-6-oxo-2-phenyl-1,6-dihydropyrimidine-4-carboxamide, ... (7 entities in total)
• 機能のキーワード: nuclease, influenza, inhibitor resistance, viral protein, viral protein-inhibitor complex, viral protein/inhibitor
• 由来する生物種: Influenza A virus (strain swl A/California/04/2009 H1N1); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 24635.67

構造登録者

Cuypers, M.G.,Slavish, P.J.,Yun, M.K.,Dubois, R.,Rankovic, Z.,White, S.W. (登録日: 2021-04-27, 公開日: 2021-10-27, 最終更新日: 2023-10-18)

• 主引用文献: Cuypers, M.G.,Slavish, P.J.,Yun, M.K.,Dubois, R.,Rankovic, Z.,White, S.W.; The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with St Jude compound AC067-19; To Be Published,

実験手法

X-RAY DIFFRACTION (2.7 Å)