7MKM
SARS-CoV-2 Spike RBD in complex with neutralizing Fab SARS2-38 (local refinement)
7MKM の概要
エントリーDOI | 10.2210/pdb7mkm/pdb |
EMDBエントリー | 23898 23899 |
分子名称 | Spike protein S1, SARS2-38 Fv heavy chain, SARS2-38 Fv light chain, ... (4 entities in total) |
機能のキーワード | glycoprotein, antibody, viral protein-immune system complex, structural genomics, center for structural genomics of infectious diseases, csgid, viral protein/immune system |
由来する生物種 | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) 詳細 |
タンパク質・核酸の鎖数 | 3 |
化学式量合計 | 45379.63 |
構造登録者 | Adams, L.J.,Fremont, D.H.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2021-04-24, 公開日: 2021-05-12, 最終更新日: 2021-12-01) |
主引用文献 | VanBlargan, L.A.,Adams, L.J.,Liu, Z.,Chen, R.E.,Gilchuk, P.,Raju, S.,Smith, B.K.,Zhao, H.,Case, J.B.,Winkler, E.S.,Whitener, B.M.,Droit, L.,Aziati, I.D.,Bricker, T.L.,Joshi, A.,Shi, P.Y.,Creanga, A.,Pegu, A.,Handley, S.A.,Wang, D.,Boon, A.C.M.,Crowe Jr., J.E.,Whelan, S.P.J.,Fremont, D.H.,Diamond, M.S. A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope. Immunity, 54:2399-2416.e6, 2021 Cited by PubMed: 34481543DOI: 10.1016/j.immuni.2021.08.016 主引用文献が同じPDBエントリー |
実験手法 | ELECTRON MICROSCOPY (3.16 Å) |
構造検証レポート
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