7MJ5

complex of human thrombin with XC-43

Summary for 7MJ5

• Entry DOI: 10.2210/pdb7mj5/pdb
• Descriptor: Putative secreted salivary protein, Thrombin light chain, Thrombin heavy chain, ... (6 entities in total)
• Functional Keywords: inhibitor, serine protease, flea, blood clotting
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 18
• Total formula weight: 227929.36

Authors

Lu, S.,Tirloni, L.,Andersen, J.F. (deposition date: 2021-04-19, release date: 2021-12-22, Last modification date: 2023-10-18)

• Primary citation: Lu, S.,Tirloni, L.,Oliveira, M.B.,Bosio, C.F.,Nardone, G.A.,Zhang, Y.,Hinnebusch, B.J.,Ribeiro, J.M.,Andersen, J.F.; Identification of a substrate-like cleavage-resistant thrombin inhibitor from the saliva of the flea Xenopsylla cheopis.; J.Biol.Chem., 297:101322-101322, 2021; PubMed: 34688666; DOI: 10.1016/j.jbc.2021.101322

Experimental method

X-RAY DIFFRACTION (2.15 Å)