7MI8
Signal subtracted reconstruction of AAA5 and AAA6 domains of dynein in the presence of a pyrazolo-pyrimidinone-based compound, Model 5
Summary for 7MI8
Entry DOI | 10.2210/pdb7mi8/pdb |
EMDB information | 23842 |
Descriptor | Fusion protein of Dynein and Endolysin (1 entity in total) |
Functional Keywords | aaa atpase, atpase inhibitor, motor protein |
Biological source | Saccharomyces cerevisiae (Baker's yeast) More |
Total number of polymer chains | 1 |
Total formula weight | 304889.88 |
Authors | Santarossa, C.C.,Coudray, N.,Urnavicius, L.,Ekiert, D.C.,Bhabha, G.,Kapoor, T.M. (deposition date: 2021-04-16, release date: 2021-05-26, Last modification date: 2024-05-29) |
Primary citation | Santarossa, C.C.,Mickolajczyk, K.J.,Steinman, J.B.,Urnavicius, L.,Chen, N.,Hirata, Y.,Fukase, Y.,Coudray, N.,Ekiert, D.C.,Bhabha, G.,Kapoor, T.M. Targeting allostery in the Dynein motor domain with small molecule inhibitors. Cell Chem Biol, 28:1460-1473.e15, 2021 Cited by PubMed: 34015309DOI: 10.1016/j.chembiol.2021.04.024 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.7 Å) |
Structure validation
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