7MHY

Human Hedgehog acyltransferase (HHAT) in complex with palmitoyl-CoA and two Fab antibody fragments

7MHY の概要

• エントリーDOI: 10.2210/pdb7mhy/pdb
• EMDBエントリー: 23836
• 分子名称: Protein-cysteine N-palmitoyltransferase HHAT, 1C06 Fab heavy chain, 1C06 Fab light chain, ... (9 entities in total)
• 機能のキーワード: mboat, goat, porcupine, acyl transferase, membrane protein, membrane enzyme, er, palmitoyl-coa, transferase-immune system complex, transferase/immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 170046.91

構造登録者

Long, S.B.,Jiang, Y. (登録日: 2021-04-16, 公開日: 2021-06-16, 最終更新日: 2021-08-25)

• 主引用文献: Jiang, Y.,Benz, T.L.,Long, S.B.; Substrate and product complexes reveal mechanisms of Hedgehog acylation by HHAT.; Science, 372:1215-1219, 2021; PubMed: 34112694; DOI: 10.1126/science.abg4998

実験手法

ELECTRON MICROSCOPY (2.7 Å)