7MCA

Structure of the S. cerevisiae origin recognition complex bound to the replication initiator Cdc6 and the ARS1 origin DNA.

7MCA の概要

• エントリーDOI: 10.2210/pdb7mca/pdb
• EMDBエントリー: 23755 23818
• 分子名称: Origin recognition complex subunit 1, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... (11 entities in total)
• 機能のキーワード: replication initiation, replication
• 由来する生物種: Saccharomyces cerevisiae (Baker's yeast); 詳細
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 527256.28

構造登録者

Feng, X.,Li, H. (登録日: 2021-04-01, 公開日: 2021-06-02, 最終更新日: 2021-08-04)

• 主引用文献: Feng, X.,Noguchi, Y.,Barbon, M.,Stillman, B.,Speck, C.,Li, H.; The structure of ORC-Cdc6 on an origin DNA reveals the mechanism of ORC activation by the replication initiator Cdc6.; Nat Commun, 12:3883-3883, 2021; PubMed: 34162887; DOI: 10.1038/s41467-021-24199-1

実験手法

ELECTRON MICROSCOPY (3.6 Å)