7MBN
Cryo-EM structure of MLL1-NCP (H3K4M) complex, mode02
Summary for 7MBN
Entry DOI | 10.2210/pdb7mbn/pdb |
EMDB information | 23739 |
Descriptor | Retinoblastoma-binding protein 5, DNA (146-MER), WD repeat-containing protein 5, ... (10 entities in total) |
Functional Keywords | mll1-ncp, h3k4 methylation, transferase, transferase-dna binding protein-dna complex, transferase/dna binding protein/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 14 |
Total formula weight | 377637.06 |
Authors | Park, S.H.,Ayoub, A.,Lee, Y.T.,Dou, Y.,Cho, U. (deposition date: 2021-04-01, release date: 2021-12-29, Last modification date: 2024-05-29) |
Primary citation | Ayoub, A.,Park, S.H.,Lee, Y.T.,Cho, U.S.,Dou, Y. Regulation of MLL1 Methyltransferase Activity in Two Distinct Nucleosome Binding Modes. Biochemistry, 61:1-9, 2022 Cited by PubMed: 34928138DOI: 10.1021/acs.biochem.1c00603 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY |
Structure validation
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