7MAS

Drug Resistant HIV-1 Protease (L10F, M46I, I50V, F53L, L63P, G73S) in Complex with DRV

Summary for 7MAS

• Entry DOI: 10.2210/pdb7mas/pdb
• Descriptor: Protease, (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE (3 entities in total)
• Functional Keywords: drug resistance, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Human immunodeficiency virus type 1 group M subtype B (HIV-1)
• Total number of polymer chains: 4
• Total formula weight: 44350.33

Authors

Lockbaum, G.J.,Schiffer, C.A. (deposition date: 2021-03-31, release date: 2022-11-09, Last modification date: 2023-10-18)

• Primary citation: Lockbaum, G.J.,Schiffer, C.A.; Drug Resistant HIV-1 Protease (L10F, M46I, I50V, F53L, L63P, G73S) in Complex with DRV; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)