7MAP

Drug Resistant HIV-1 Protease (L10I, V32I, L33F, K45I, M46I, I50V, A71V, V82I, I84V) in Complex with DRV

7MAP の概要

• エントリーDOI: 10.2210/pdb7map/pdb
• 分子名称: Protease, (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE (3 entities in total)
• 機能のキーワード: drug resistance, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Human immunodeficiency virus type 1 group M subtype B (HIV-1)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 22267.35

構造登録者

Lockbaum, G.J.,Schiffer, C.A. (登録日: 2021-03-31, 公開日: 2022-11-09, 最終更新日: 2023-10-18)

• 主引用文献: Lockbaum, G.J.,Schiffer, C.A.; Drug Resistant HIV-1 Protease (L10I, V32I, L33F, K45I, M46I, I50V, A71V, V82I, I84V) in Complex with DRV; To Be Published,

実験手法

X-RAY DIFFRACTION (1.951 Å)