7MAB

HIV-1 Protease (I84V) in Complex with GS-8374

7MAB の概要

• エントリーDOI: 10.2210/pdb7mab/pdb
• 分子名称: Protease, SULFATE ION, DIETHYL ({4-[(2S,3R)-2-({[(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YLOXY]CARBONYL}AMINO)-3-HYDROXY-4-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}BUTYL]PHENOXY}METHYL)PHOSPHONATE, ... (4 entities in total)
• 機能のキーワード: hiv, nl4-3 protease, drug resistance, protease inhibitor, complex, hydrolase inhibitor complex, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Human immunodeficiency virus 1 (HIV-1)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 22844.72

構造登録者

Lockbaum, G.J.,Schiffer, C.A. (登録日: 2021-03-31, 公開日: 2022-04-27, 最終更新日: 2023-10-18)

• 主引用文献: Lockbaum, G.J.,Schiffer, C.A.; HIV-1 Protease (I84V) in Complex with GS-8374; To Be Published,

実験手法

X-RAY DIFFRACTION (1.879 Å)