7M9F
Structure of the wild-type native full-length HIV-1 capsid protein in complex with ZW-1261
Summary for 7M9F
Entry DOI | 10.2210/pdb7m9f/pdb |
Descriptor | HIV-1 capsid protein, N-(4-chlorophenyl)-Nalpha-[(5-hydroxy-1H-indol-3-yl)acetyl]-N-methyl-L-phenylalaninamide, IODIDE ION, ... (4 entities in total) |
Functional Keywords | hiv-1 capsid protein, hexamer, ca-targeting antiviral, viral protein |
Biological source | Human immunodeficiency virus 1 |
Total number of polymer chains | 1 |
Total formula weight | 26726.89 |
Authors | Kirby, K.A.,Sarafianos, S.G. (deposition date: 2021-03-31, release date: 2022-04-06, Last modification date: 2023-10-18) |
Primary citation | Sun, Q.,Levy, R.M.,Kirby, K.A.,Wang, Z.,Sarafianos, S.G.,Deng, N. Molecular Dynamics Free Energy Simulations Reveal the Mechanism for the Antiviral Resistance of the M66I HIV-1 Capsid Mutation. Viruses, 13:-, 2021 Cited by PubMed: 34063519DOI: 10.3390/v13050920 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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