7M9F

Structure of the wild-type native full-length HIV-1 capsid protein in complex with ZW-1261

7M9F の概要

• エントリーDOI: 10.2210/pdb7m9f/pdb
• 分子名称: HIV-1 capsid protein, N-(4-chlorophenyl)-Nalpha-[(5-hydroxy-1H-indol-3-yl)acetyl]-N-methyl-L-phenylalaninamide, IODIDE ION, ... (4 entities in total)
• 機能のキーワード: hiv-1 capsid protein, hexamer, ca-targeting antiviral, viral protein
• 由来する生物種: Human immunodeficiency virus 1
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 26726.89

構造登録者

Kirby, K.A.,Sarafianos, S.G. (登録日: 2021-03-31, 公開日: 2022-04-06, 最終更新日: 2023-10-18)

• 主引用文献: Sun, Q.,Levy, R.M.,Kirby, K.A.,Wang, Z.,Sarafianos, S.G.,Deng, N.; Molecular Dynamics Free Energy Simulations Reveal the Mechanism for the Antiviral Resistance of the M66I HIV-1 Capsid Mutation.; Viruses, 13:-, 2021; PubMed: 34063519; DOI: 10.3390/v13050920

実験手法

X-RAY DIFFRACTION (2.7 Å)