7M1Q
Human ABCA4 structure in complex with N-ret-PE
Summary for 7M1Q
Entry DOI | 10.2210/pdb7m1q/pdb |
EMDB information | 23618 |
Descriptor | Retinal-specific phospholipid-transporting ATPase ABCA4, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | abc transporter, importer, membrane protein, transport protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 260061.90 |
Authors | Scortecci, J.F.,Van Petegem, F.,Molday, R.S. (deposition date: 2021-03-14, release date: 2021-09-08, Last modification date: 2021-10-20) |
Primary citation | Scortecci, J.F.,Molday, L.L.,Curtis, S.B.,Garces, F.A.,Panwar, P.,Van Petegem, F.,Molday, R.S. Cryo-EM structures of the ABCA4 importer reveal mechanisms underlying substrate binding and Stargardt disease. Nat Commun, 12:5902-5902, 2021 Cited by PubMed: 34625547DOI: 10.1038/s41467-021-26161-7 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.92 Å) |
Structure validation
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