7M1P

Human ABCA4 structure in the unbound state

7M1P の概要

• エントリーDOI: 10.2210/pdb7m1p/pdb
• EMDBエントリー: 23617
• 分子名称: Retinal-specific phospholipid-transporting ATPase ABCA4, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: abc transporter, importer, membrane protein, transport protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 258787.92

構造登録者

Scortecci, J.F.,Van Petegem, F.,Molday, R.S. (登録日: 2021-03-14, 公開日: 2021-09-08, 最終更新日: 2021-10-20)

• 主引用文献: Scortecci, J.F.,Molday, L.L.,Curtis, S.B.,Garces, F.A.,Panwar, P.,Van Petegem, F.,Molday, R.S.; Cryo-EM structures of the ABCA4 importer reveal mechanisms underlying substrate binding and Stargardt disease.; Nat Commun, 12:5902-5902, 2021; PubMed: 34625547; DOI: 10.1038/s41467-021-26161-7

実験手法

ELECTRON MICROSCOPY (3.6 Å)