7M08
Post-catalytic nicked complex of DNA Polymerase Lambda with bound 1-nt gapped SSB substrate and incoming dUMPNPP
Summary for 7M08
Entry DOI | 10.2210/pdb7m08/pdb |
Descriptor | DNA polymerase lambda, DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), DNA (5'-D(*CP*AP*GP*TP*AP*CP*T)-3'), ... (10 entities in total) |
Functional Keywords | nonhomologous end-joining, base excision repair, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 45499.69 |
Authors | Kaminski, A.M.,Bebenek, K.,Pedersen, L.C.,Kunkel, T.A. (deposition date: 2021-03-10, release date: 2022-03-16, Last modification date: 2023-10-18) |
Primary citation | Kaminski, A.M.,Bebenek, K.,Kunkel, T.A.,Pedersen, L.C. Comprehensive structural survey of DNA double-strand break synapsis by DNA Polymerase Lambda Not Published, |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
Download full validation report