7LY9

Cryo-EM structure of 2909 Fab in complex with 3BNC117 Fab and CAP256.wk34.c80 SOSIP.RnS2 N160K HIV-1 Env trimer

7LY9 の概要

• エントリーDOI: 10.2210/pdb7ly9/pdb
• EMDBエントリー: 23589
• 分子名称: 2909 Light Chain, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• 機能のキーワード: cap256, v1v2, v2-apex, sosip, vaccine, tys, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 14
• 化学式量合計: 422724.33

構造登録者

Gorman, J.,Kwong, P.D. (登録日: 2021-03-06, 公開日: 2021-08-18, 最終更新日: 2021-11-24)

• 主引用文献: Lee, M.,Changela, A.,Gorman, J.,Rawi, R.,Bylund, T.,Chao, C.W.,Lin, B.C.,Louder, M.K.,Olia, A.S.,Zhang, B.,Doria-Rose, N.A.,Zolla-Pazner, S.,Shapiro, L.,Chuang, G.Y.,Kwong, P.D.; Extended antibody-framework-to-antigen distance observed exclusively with broad HIV-1-neutralizing antibodies recognizing glycan-dense surfaces.; Nat Commun, 12:6470-6470, 2021; PubMed: 34753907; DOI: 10.1038/s41467-021-26579-z

実験手法

ELECTRON MICROSCOPY (3.91 Å)