7LXH
Bacillus cereus DNA glycosylase AlkD bound to a CC1065-adenine nucleobase adduct and DNA containing an abasic site
Summary for 7LXH
Entry DOI | 10.2210/pdb7lxh/pdb |
Related | 5UUG 7LXJ |
Descriptor | DNA-7-methylguanine glycosylase, DNA (5'-D(*AP*GP*CP*AP*AP*(ORP)P*GP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*CP*TP*TP*TP*GP*C)-3'), ... (6 entities in total) |
Functional Keywords | dna repair, base excision repair, antibiotic self-resistance, bulky dna adduct, secondary metabolite, dna binding protein, hydrolase-dna-antibiotic complex, hydrolase/dna/antibiotic |
Biological source | Bacillus cereus More |
Total number of polymer chains | 3 |
Total formula weight | 34851.54 |
Authors | Mullins, E.A.,Eichman, B.F. (deposition date: 2021-03-03, release date: 2021-11-17, Last modification date: 2023-10-18) |
Primary citation | Mullins, E.A.,Dorival, J.,Tang, G.L.,Boger, D.L.,Eichman, B.F. Structural evolution of a DNA repair self-resistance mechanism targeting genotoxic secondary metabolites. Nat Commun, 12:6942-6942, 2021 Cited by PubMed: 34836957DOI: 10.1038/s41467-021-27284-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.667 Å) |
Structure validation
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