7LWH
Human neurofibromin 2/merlin residues 1-339 in complex with LATS1
Summary for 7LWH
Entry DOI | 10.2210/pdb7lwh/pdb |
Descriptor | Merlin, Serine/threonine-protein kinase LATS1, IMIDAZOLE, ... (5 entities in total) |
Functional Keywords | actin, cancer, cell adhesion, cell junction, cell migration, cell signaling, inositol phospholipid, neurofibromatosis type 2, plasma membrane |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 43159.94 |
Authors | Primi, M.C.,Rangarajan, E.S.,Izard, T. (deposition date: 2021-03-01, release date: 2021-08-11, Last modification date: 2023-10-18) |
Primary citation | Primi, M.C.,Rangarajan, E.S.,Patil, D.N.,Izard, T. Conformational flexibility determines the Nf2/merlin tumor suppressor functions. Matrix Biol Plus, 12:100074-100074, 2021 Cited by PubMed: 34337379DOI: 10.1016/j.mbplus.2021.100074 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.606 Å) |
Structure validation
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