7LWB

Crystal Structure of phospho-Rab8a with the RH2 domain (117-165) of RILPL2

7LWB の概要

• エントリーDOI: 10.2210/pdb7lwb/pdb
• 分子名称: Ras-related protein Rab-8A, RILP-like protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
• 機能のキーワード: membrane trafficking, rab8a, effector, rab-interacting lysosomal protein-like 2, macromolecular complex, lrrk2 kinase, switch 2, phosphorylation ciliogenesis, signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 27825.71

構造登録者

Waschbusch, D.,Khan, A.R. (登録日: 2021-02-28, 公開日: 2021-03-10, 最終更新日: 2023-10-18)

• 主引用文献: Waschbusch, D.,Purlyte, E.,Khan, A.R.; Dual arginine recognition of LRRK2 phosphorylated Rab GTPases.; Biophys.J., 120:1846-1855, 2021; PubMed: 33887226; DOI: 10.1016/j.bpj.2021.03.030

実験手法

X-RAY DIFFRACTION (1.9 Å)