7LW8
Human Exonuclease 5 crystal structure in complex with a ssDNA
Summary for 7LW8
Entry DOI | 10.2210/pdb7lw8/pdb |
Descriptor | Exonuclease V, DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), IRON/SULFUR CLUSTER, ... (6 entities in total) |
Functional Keywords | hydrolase, hydrolase-dna complex, hydrolase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 43007.17 |
Authors | Tsai, C.L.,Tainer, J.A. (deposition date: 2021-02-28, release date: 2021-07-14, Last modification date: 2023-10-18) |
Primary citation | Hambarde, S.,Tsai, C.L.,Pandita, R.K.,Bacolla, A.,Maitra, A.,Charaka, V.,Hunt, C.R.,Kumar, R.,Limbo, O.,Le Meur, R.,Chazin, W.J.,Tsutakawa, S.E.,Russell, P.,Schlacher, K.,Pandita, T.K.,Tainer, J.A. EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart. Mol.Cell, 81:2989-, 2021 Cited by PubMed: 34197737DOI: 10.1016/j.molcel.2021.05.027 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.88 Å) |
Structure validation
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