7LUC

Cryo-EM structure of RSV preF bound by Fabs 32.4K and 01.4B

7LUC の概要

• エントリーDOI: 10.2210/pdb7luc/pdb
• EMDBエントリー: 23520
• 分子名称: Fusion glycoprotein F0, 01.4B Fab Heavy chain, 01.4B Fab Light chain, ... (5 entities in total)
• 機能のキーワード: rsv, viral fusogen, fusion protein, antibody, immune system, immune system-viral protein complex, immune system/viral protein
• 由来する生物種: Respiratory syncytial virus; 詳細
• タンパク質・核酸の鎖数: 15
• 化学式量合計: 330223.85

構造登録者

Wrapp, D.,McLellan, J.S. (登録日: 2021-02-22, 公開日: 2021-04-21, 最終更新日: 2021-04-28)

• 主引用文献: Mukhamedova, M.,Wrapp, D.,Shen, C.H.,Gilman, M.S.A.,Ruckwardt, T.J.,Schramm, C.A.,Ault, L.,Chang, L.,Derrien-Colemyn, A.,Lucas, S.A.M.,Ransier, A.,Darko, S.,Phung, E.,Wang, L.,Zhang, Y.,Rush, S.A.,Madan, B.,Stewart-Jones, G.B.E.,Costner, P.J.,Holman, L.A.,Hickman, S.P.,Berkowitz, N.M.,Doria-Rose, N.A.,Morabito, K.M.,DeKosky, B.J.,Gaudinski, M.R.,Chen, G.L.,Crank, M.C.,Misasi, J.,Sullivan, N.J.,Douek, D.C.,Kwong, P.D.,Graham, B.S.,McLellan, J.S.,Mascola, J.R.; Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses.; Immunity, 54:769-780.e6, 2021; PubMed: 33823129; DOI: 10.1016/j.immuni.2021.03.004

実験手法

ELECTRON MICROSCOPY (3.21 Å)