7LT0
Hsp90a N-terminal inhibitor
Summary for 7LT0
Entry DOI | 10.2210/pdb7lt0/pdb |
Descriptor | Heat shock protein HSP 90-alpha, (1,3-dihydro-2H-isoindol-2-yl){3-[(3,4-dimethylphenyl)sulfanyl]-4-hydroxyphenyl}methanone (3 entities in total) |
Functional Keywords | inhibitor, hsp90, chaperone |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 33875.72 |
Authors | |
Primary citation | Mishra, S.J.,Khandelwal, A.,Banerjee, M.,Balch, M.,Peng, S.,Davis, R.E.,Merfeld, T.,Munthali, V.,Deng, J.,Matts, R.L.,Blagg, B.S.J. Selective Inhibition of the Hsp90 alpha Isoform. Angew.Chem.Int.Ed.Engl., 60:10547-10551, 2021 Cited by PubMed: 33621416DOI: 10.1002/anie.202015422 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.697 Å) |
Structure validation
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