7LR9
Crystal structure of KPC-2 S70G/T215P mutant with hydrolyzed imipenem
Summary for 7LR9
Entry DOI | 10.2210/pdb7lr9/pdb |
Descriptor | Carbapenem-hydrolyzing beta-lactamase KPC, (2R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-(2-methanimidamidoethylsulfanyl)-2,3-dihydro-1H-pyrrole -5-carboxylic acid (3 entities in total) |
Functional Keywords | kpc, carbapenemase, beta-lactamase, hydrolase, antibiotic resistance, enzyme, beta-lactam, antibiotics, hydrolase-antibiotic complex, hydrolase/antibiotic |
Biological source | Klebsiella pneumoniae |
Total number of polymer chains | 2 |
Total formula weight | 57264.54 |
Authors | Furey, I.,Palzkill, T.,Hu, L.,Prasad, B.V.V. (deposition date: 2021-02-16, release date: 2022-08-10, Last modification date: 2023-10-18) |
Primary citation | Furey, I.M.,Palzkill, T. Crystal structure of KPC-2 T215P mutant To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.47 Å) |
Structure validation
Download full validation report