7LR4

Complex of Fab 2/1.12 with domain 3 of P. berghei HAP2

7LR4 の概要

• エントリーDOI: 10.2210/pdb7lr4/pdb
• 分子名称: D3_2/1.12 Fab heavy chain, D3_2/1.12 Fab light chain, Hapless 2, ... (6 entities in total)
• 機能のキーワード: transmission-blocking malaria vaccine, membrane fusion, gamete fusogen, monoclonal antibody, surfactant protein, cell adhesion, cell adhesion-immune system complex, cell adhesion/immune system
• 由来する生物種: Mus musculus; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 124413.22

構造登録者

Feng, J.,Dong, X.C.,Su, Y.,Lu, X.F.,Springer, T.A. (登録日: 2021-02-15, 公開日: 2021-12-15, 最終更新日: 2023-10-18)

• 主引用文献: Feng, J.,Dong, X.,DeCosta, A.,Su, Y.,Angrisano, F.,Sala, K.A.,Blagborough, A.M.,Lu, C.,Springer, T.A.; Structural basis of malaria transmission blockade by a monoclonal antibody to gamete fusogen HAP2.; Elife, 10:-, 2021; PubMed: 34939934; DOI: 10.7554/eLife.74707

実験手法

X-RAY DIFFRACTION (2.1 Å)