7LPO
Crystal structure of Cryptococcus neoformans sterylglucosidase 1 with tris
Summary for 7LPO
Entry DOI | 10.2210/pdb7lpo/pdb |
Descriptor | Cytoplasmic protein, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | glucosidase, sterylglucosidase, hydrolase |
Biological source | Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii) More |
Total number of polymer chains | 4 |
Total formula weight | 357305.07 |
Authors | Pereira de Sa, N.,Del Poeta, M.,Airola, M.V. (deposition date: 2021-02-12, release date: 2021-09-01, Last modification date: 2024-05-22) |
Primary citation | Pereira de Sa, N.,Taouil, A.,Kim, J.,Clement, T.,Hoffmann, R.M.,Burke, J.E.,Rizzo, R.C.,Ojima, I.,Del Poeta, M.,Airola, M.V. Structure and inhibition of Cryptococcus neoformans sterylglucosidase to develop antifungal agents. Nat Commun, 12:5885-5885, 2021 Cited by PubMed: 34620873DOI: 10.1038/s41467-021-26163-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.13 Å) |
Structure validation
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