7LPO

Crystal structure of Cryptococcus neoformans sterylglucosidase 1 with tris

Summary for 7LPO

Entry DOI	10.2210/pdb7lpo/pdb
Descriptor	Cytoplasmic protein, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	glucosidase, sterylglucosidase, hydrolase
Biological source	Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii) More
Total number of polymer chains	4
Total formula weight	357305.07
Authors	Pereira de Sa, N.,Del Poeta, M.,Airola, M.V. (deposition date: 2021-02-12, release date: 2021-09-01, Last modification date: 2024-05-22)
Primary citation	Pereira de Sa, N.,Taouil, A.,Kim, J.,Clement, T.,Hoffmann, R.M.,Burke, J.E.,Rizzo, R.C.,Ojima, I.,Del Poeta, M.,Airola, M.V. Structure and inhibition of Cryptococcus neoformans sterylglucosidase to develop antifungal agents. Nat Commun, 12:5885-5885, 2021 Cited by PubMed: 34620873 DOI: 10.1038/s41467-021-26163-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.13 Å)

Structure validation