7LPN

Cryo-EM structure of llama J3 VHH antibody in complex with HIV-1 Env BG505 DS-SOSIP.664

Summary for 7LPN

Entry DOI	10.2210/pdb7lpn/pdb
EMDB information	23480
Descriptor	HIV-1 Envelope Glycoprotein BG505 SOSIP.664 gp41, Envelope glycoprotein gp160, J3 VHH, ... (8 entities in total)
Functional Keywords	cd4, hiv-1, sosip, vaccine, immune system, llama, viral protein
Biological source	Human immunodeficiency virus 1 (HIV-1) More
Total number of polymer chains	9
Total formula weight	276485.27
Authors	Gorman, J.,Kwong, P.D. (deposition date: 2021-02-12, release date: 2022-02-23, Last modification date: 2023-03-29)
Primary citation	Zhou, T.,Chen, L.,Gorman, J.,Wang, S.,Kwon, Y.D.,Lin, B.C.,Louder, M.K.,Rawi, R.,Stancofski, E.D.,Yang, Y.,Zhang, B.,Quigley, A.F.,McCoy, L.E.,Rutten, L.,Verrips, T.,Weiss, R.A.,Doria-Rose, N.A.,Shapiro, L.,Kwong, P.D. Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site. Structure, 30:862-875.e4, 2022 Cited by PubMed: 35413243 DOI: 10.1016/j.str.2022.03.012 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.61 Å)

Structure validation