7LOP

Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CV05-163 and CR3022

Summary for 7LOP

• Entry DOI: 10.2210/pdb7lop/pdb
• Descriptor: CR3022 Fab heavy chain, CR3022 Fab light chain, Spike protein S1, ... (7 entities in total)
• Functional Keywords: sars-cov-2, receptor binding domain, coronavirus, covid-19, antibody, fab, immune system, viral protein-immune system complex, viral protein/immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 10
• Total formula weight: 243794.73

Authors

Yuan, M.,Zhu, X.,Wilson, I.A. (deposition date: 2021-02-10, release date: 2021-03-03, Last modification date: 2023-10-18)

• Primary citation: Yuan, M.,Huang, D.,Lee, C.D.,Wu, N.C.,Jackson, A.M.,Zhu, X.,Liu, H.,Peng, L.,van Gils, M.J.,Sanders, R.W.,Burton, D.R.,Reincke, S.M.,Pruss, H.,Kreye, J.,Nemazee, D.,Ward, A.B.,Wilson, I.A.; Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants.; Science, 373:818-823, 2021; PubMed: 34016740; DOI: 10.1126/science.abh1139

Experimental method

X-RAY DIFFRACTION (2.246 Å)