7LNF

3'-deoxy modification at 3' end of RNA primer complex with guanosine dinucleotide ligand G(5')ppp(5')G

7LNF の概要

• エントリーDOI: 10.2210/pdb7lnf/pdb
• 分子名称: RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*(GDO))-3'), [(1R,3R,4R,7S)-7-HYDROXY-3-(5-METHYLCYTOSIN-1-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL DIHYDROGEN PHOSPHATE, [(1R,3R,4R,7S)-7-HYDROXY-3-(GUANIN-9-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL DIHYDROGEN PHOSPHATE, ... (9 entities in total)
• 機能のキーワード: rna, nonenzymatic rna extension
• 由来する生物種: synthetic construct
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 14114.83

構造登録者

Fang, Z.,Giurgiu, C.,Szostak, J.W. (登録日: 2021-02-07, 公開日: 2021-09-08, 最終更新日: 2023-10-18)

• 主引用文献: Giurgiu, C.,Fang, Z.,Aitken, H.R.M.,Kim, S.C.,Pazienza, L.,Mittal, S.,Szostak, J.W.; Structure-Activity Relationships in Nonenzymatic Template-Directed RNA Synthesis.; Angew.Chem.Int.Ed.Engl., 60:22925-22932, 2021; PubMed: 34428345; DOI: 10.1002/anie.202109714

実験手法

X-RAY DIFFRACTION (1.652 Å)