7LJ9

Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate

Summary for 7LJ9

Entry DOI	10.2210/pdb7lj9/pdb
Related	6ui9
EMDB information	23389
Descriptor	ATP-citrate synthase, OXALOACETATE ION, ACETYL COENZYME *A (3 entities in total)
Functional Keywords	lyase
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	485401.46
Authors	Wei, X.,Marmorstein, R. (deposition date: 2021-01-28, release date: 2021-03-31, Last modification date: 2024-05-29)
Primary citation	Wei, X.,Marmorstein, R. Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase. Nat.Struct.Mol.Biol., 28:639-641, 2021 Cited by PubMed: 34294921 DOI: 10.1038/s41594-021-00625-2 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3 Å)

Structure validation