7LF9

Structure of Hyperglycosylated Human IgG1 Fc (Fc329)

7LF9 の概要

• エントリーDOI: 10.2210/pdb7lf9/pdb
• 分子名称: IgG1 Fc (Fc329), 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: effector, igg, antibody, fc, signaling protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 55445.05

構造登録者

Fields, J.K.,Sundberg, E.J. (登録日: 2021-01-15, 公開日: 2021-01-27, 最終更新日: 2023-10-18)

• 主引用文献: Fields, J.K.,Sundberg, E.J.; Silent Antibodies: Generation of Hyperglycosylated FCs to Ablate Effector Functions; To Be Published,

実験手法

X-RAY DIFFRACTION (2.2 Å)