7LCV

Factor H enhancing human antibody fragment (Fab) to meningococcal Factor H binding protein

Summary for 7LCV

• Entry DOI: 10.2210/pdb7lcv/pdb
• Related: 7KE1 7KET
• Descriptor: Immunoglobulin heavy chain Fd fragment, Immunoglobulin kappa light chain, Factor H binding protein, ... (5 entities in total)
• Functional Keywords: human, antibody, fab, meningococcal vaccine, factor h binding protein, complex, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 75688.92

Authors

Beernink, P.T.,Sands, N. (deposition date: 2021-01-11, release date: 2021-06-09, Last modification date: 2023-10-18)

• Primary citation: Sands, N.A.,Beernink, P.T.; Two human antibodies to a meningococcal serogroup B vaccine antigen enhance binding of complement Factor H by stabilizing the Factor H binding site.; Plos Pathog., 17:e1009655-e1009655, 2021; PubMed: 34125873; DOI: 10.1371/journal.ppat.1009655

Experimental method

X-RAY DIFFRACTION (1.7 Å)