7LB0

Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ZS1-295

7LB0 の概要

• エントリーDOI: 10.2210/pdb7lb0/pdb
• 分子名称: Transcription initiation factor TFIID subunit 1, 1-{6-[(3R)-3-methylmorpholin-4-yl]-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl}cyclopropane-1-sulfonamide, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: bromodomain, taf1, tbp, transcription, general transcription factor iid, tfiid, tf250, non-bet, atr, kinase, gene regulation
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 31444.81

構造登録者

Karim, M.R.,Schonbrunn, E. (登録日: 2021-01-07, 公開日: 2021-07-14, 最終更新日: 2023-10-18)

• 主引用文献: Karim, M.R.,Schonbrunn, E.; Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ZS1-295; To Be Published,

実験手法

X-RAY DIFFRACTION (2.33 Å)